During a significant 55% increase in chikungunya cases this year, the health department intends to perform genetic sequencing on samples to identify potential mutations. Uncommon symptoms like hyperpigmentation and neurological complications have surfaced. The health department in Mumbai is responding to the nearly 55% spike in chikungunya cases this year compared to the previous year by planning to analyze positive samples through genomic sequencing for potential viral mutations. Officials stated that rare symptoms such as hyperpigmentation and neurological issues have been observed, although they are not entirely new and are quite uncommon. These symptoms could manifest in chikungunya patients with co-existent dengue or Japanese encephalitis infections, as explained by Dr. Mahendra Jagtap, the joint director of the vector control program. To investigate the abrupt increase in chikungunya cases from 1,702 in 2023 to 2,643 in 2024, a rapid action team has been established and has released directives for the collection and analysis of samples. Specifically, samples showing neurological symptoms like paralysis and hyperpigmentation are to be sent to the National Institute of Virology and B J Medical College in Pune. The team aims to explore potential co-infection and conduct genomic sequencing to identify any mutations. Dr. Rajesh Karyakarte emphasized that genomic sequencing will be pivotal in detecting mutations and assessing the situation effectively.The doctor emphasized the importance of sequencing samples promptly, especially from ICU patients or those with severe symptoms. Private sector hospital doctors reported a significant increase in chikungunya cases this year, with some patients requiring hospitalization for 10 to 15 days due to high fever and neurological complications. Children have also been affected, with cases including an eight-month-old boy admitted to SRCC Children's Hospital in August. At Surya Children's Hospital, Dr. Bhupendra Avasthi noted that children born to chikungunya-positive mothers may exhibit hyperpigmentation, a known symptom of the disease.